Advances in nano drug delivery

Scientists at The Methodist Hospital Research Institute have found a possible way to fool the immune system to prevent it from recognizing and destroying nanoparticles before they deliver their drug payloads.

“Our goal was to make a particle that is camouflaged within our bodies and escapes the surveillance of the immune system to reach its target undiscovered,” said Department of Medicine Co–Chair Ennio Tasciotti, Ph.D., the study’s principal investigator.

They accomplished that by using lipids and proteins present on the membrane of immune system leukocytes (white blood cells) to coat a nanoparticle to make the body’s immune system recognize these nanoparticles as its own.

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• Nanotechnology

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